Emergency Response Employees Disease Protection Act of 2000 - Requires the Secretary of Health and Human Services to study and report to Congress on: (1) an estimate of the prevalence of hepatitis C among designated emergency response employees in the United States; and (2) the likely means through which such employees become infected with such disease in the course of performing their duties. Defines "designated emergency response employees" as firefighters, paramedics, and emergency medical technicians who are employees or volunteers of units of local government.

Directs the Secretary to make grants to qualifying local governments for purposes of carrying out demonstration projects that: (1) train such employees in minimizing the risk of infection of hepatitis C in performing their duties; and (2) test such employees for infection with, and treat them for, the disease. Defines "qualifying local government" as a local government whose population of designated emergency response employees has a prevalence of hepatitis C that is not less than 200 percent of the national average for the prevalence of such disease in such populations. Conditions such grants on the local government maintaining confidentiality of information regarding testing or treatment. Requires the Secretary to report to Congress on evaluations of such projects and provide recommendations for administrative or legislative initiatives regarding project activities.

Authorizes appropriations.